Python path to encodings not found / fatal error

[FMassion]

I have tried severaltimes to get python running correctly. Today 2 hours for nothing. Error message:
Fatal Python error: Py_Initialize: unable to load the file system codec
ImportError: No module named ‘encodings’
The Environment Variables are correct. I even added the path to the lib directory and to the encodings directrory.
I use python 3.7 installed by Anaconda.
I tried also to build a new system with the path hardcoded in it, but to no avail.
I have tha latest version of ST installed on a windows system.