When using multiple cursors on a single line, performance dramatically slows down as the line becomes longer. This gets to the point where my entire PC will freeze for multiple seconds after every input.
An easy test is to create a short line, then add 10-15+ cursors on that line and begin typing. After a few sentences, sublime will slow down until it grinds to a near halt as the line gets longer.
Sublime jumps up to ~30-40% Cpu usage during the freezes vs 0% - 5% during normal use.