It would be great if we could drag and drop tabs at the window edges and have them create the pane layouts. Like the adobe suite apps have. A blue highlight could show at the edge you're about to drop it on. And you could just drag the tabs back to one layout to remove them.
Vote here - http://sublimetext.userecho.com/feedback/27876-/
I think this would be a great feature!
Does the developer check the voting site?
I have found that Alt+Shit 1,2,3,4,5 is a really nice way to quickly change layout, and does everything I need it to.