I found that every so often, CPU Usage for Sublime Text 3 on macOS spikes and renders the application unusable. It wasn’t related to indexing and I would have to reboot the machine in order to resolve the issue.
The past few times I’ve noticed the CPU spike, it corresponds with similar usage spikes with an fsavd process. (This is from F-Secure Computer Protection.)
It turns out that this Sublime Text CPU spike occurs when F-Secure Computer Protection is updating its database.
Strange issue. Not sure why the database update would impact Sublime Text 3.